What is Lidocaine?
We used lidocaine because it’s a super cool compound. And, while going through the proper FDA channels to ensure we can offer the strongest, most efficacious, and safest numbing cream allowed, some members of our team thought it’d be worthwhile to share some info on what lidocaine is and how it works.
Lidocaine was originally synthesized in 1943 as a local anesthetic, and is chemically known as (get ready):
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide or, C14H22N2O for short. Yeah, we know. “Lidocaine” is way better.
It works by blocking the neuron impulse channels associated with the sodium ion (Na+), and when enough of these sodium channels are blocked, the neurons responsible for sending pain signals to the brain cease to depolarize, which means the cells’ membranes don’t activate like they normally would. This process not only stops the signals already on their way to the brain, but prevents future ones from happening at all.
It’s also got a half-life of between 90 and 120 minutes, which means its effects wear off after a few hours.